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About Prevnar 13About Prevnar 13Mechanism of ActionSerotype coverageIncidence of IPD and Colonization dataExperienceImmunogenicityDosingDosingDosingEfficacy and Safety ProfileEfficacy and Safety ProfileEfficacy profileSafety profileGuidelinesGuidelinesGuidelinesResourcesResourcesMaterialsVideos
Product MonographImportant Safety Information 
Mechanism of Action

Prevnar 13 provides an enhanced antibody response with 6 additional polysaccharides (1, 3, 5, 6A, 7F, 19A).1

Polysaccharide Vaccine1

The immune response to a pure polysaccharide vaccine involves the production of antibodies by B-cells, and is typically T-cell independent.1

Conjugate Polysaccharide

Protein conjugation changes the immune response from T-cell independent to T-cell dependent, enhancing antibody response via memory B-cells and inducing immune memory.1

Conjugated polysaccharide vaccines, such as Prevnar 13, stimulate the immune system to generate:1*

  • High-affinity antibodies
  • Long-lived B-cells
  • Immune memory
 Learn more about Prevnar 13’s enhanced antibody response  * Comparative clinical significance is unknown.Reference:Prevnar® 13 Product Monograph. Pfizer Canada ULC. 2022. About Prevnar 13
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